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Applications of Signal Processing Techniques to Bioinformatics, Genomics, and Proteomics

Guest Editors: Erchin Serpedin, Ulisses Braga-Neto, Javier Garcia-Frias and Yufei Huang

  1. Research Article

    Clustering of Gene Expression Data Based on Shape Similarity

    A method for gene clustering from expression profiles using shape information is presented. The conventional clustering approaches such as K-means assume that genes with similar functions have similar expressi...

    Travis J Hestilow and Yufei Huang

    EURASIP Journal on Bioinformatics and Systems Biology 2009 2009:195712

    Published on: 4 March 2009

  2. Research Article

    Identifying Genes Involved in Cyclic Processes by Combining Gene Expression Analysis and Prior Knowledge

    Based on time series gene expressions, cyclic genes can be recognized via spectral analysis and statistical periodicity detection tests. These cyclic genes are usually associated with cyclic biological process...

    Wentao Zhao, Erchin Serpedin and Edward R. Dougherty

    EURASIP Journal on Bioinformatics and Systems Biology 2009 2009:683463

    Published on: 3 March 2009

  3. Research Article

    Spectral Preprocessing for Clustering Time-Series Gene Expressions

    Based on gene expression profiles, genes can be partitioned into clusters, which might be associated with biological processes or functions, for example, cell cycle, circadian rhythm, and so forth. This paper ...

    Wentao Zhao, Erchin Serpedin and Edward R. Dougherty

    EURASIP Journal on Bioinformatics and Systems Biology 2009 2009:713248

    Published on: 24 February 2009

  4. Research Article

    Intervention in Context-Sensitive Probabilistic Boolean Networks Revisited

    An approximate representation for the state space of a context-sensitive probabilistic Boolean network has previously been proposed and utilized to devise therapeutic intervention strategies. Whereas the full ...

    Babak Faryabi, Golnaz Vahedi, Jean-Francois Chamberland, Aniruddha Datta and EdwardR Dougherty

    EURASIP Journal on Bioinformatics and Systems Biology 2009 2009:360864

    Published on: 11 February 2009

  5. Research Article

    How to Improve Postgenomic Knowledge Discovery Using Imputation

    While microarrays make it feasible to rapidly investigate many complex biological problems, their multistep fabrication has the proclivity for error at every stage. The standard tactic has been to either ignor...

    Muhammad Shoaib B Sehgal, Iqbal Gondal, Laurence S Dooley and Ross Coppel

    EURASIP Journal on Bioinformatics and Systems Biology 2009 2009:717136

    Published on: 11 January 2009

  6. Research Article

    Compressive Sensing DNA Microarrays

    Compressive sensing microarrays (CSMs) are DNA-based sensors that operate using group testing and compressive sensing (CS) principles. In contrast to conventional DNA microarrays, in which each genetic sensor ...

    Wei Dai, Mona A Sheikh, Olgica Milenkovic and Richard G Baraniuk

    EURASIP Journal on Bioinformatics and Systems Biology 2008 2009:162824

    Published on: 22 December 2008