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10th Anniversary Collection

Since its launch in 2004, Journal of Neuroinflammation has established itself as a premier destination for research focused on innate immunological responses of the nervous system. We are celebrating our success over the last ten years with a series of exciting reviews that mark key accomplishments within the field over this period, whilst also looking forward to advances on the horizon.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process.

View all collections published in Journal of Neuroinflammation

  1. An increasing number of studies show that the activation of the innate immune system and inflammatory mechanisms play an important role in the pathogenesis of numerous diseases. The innate immune system is pre...

    Authors: Giorgio Santoni, Claudio Cardinali, Maria Beatrice Morelli, Matteo Santoni, Massimo Nabissi and Consuelo Amantini
    Citation: Journal of Neuroinflammation 2015 12:21
    Content type: Review Published on:

  2. Recent phase II and III studies with intravenous immunoglobulin (IVIG) in patients with Alzheimer’s disease (AD) did not find evidence for the slowing of AD progression compared to placebo-treated patients, in...

    Authors: David A Loeffler
    Citation: Journal of Neuroinflammation 2014 11:198
    Content type: Review Published on:

    The Erratum to this article has been published in Journal of Neuroinflammation 2015 12:68

  3. Similar to peripheral immune/inflammatory cells, neuroglial cells appear to rely on calcineurin (CN) signaling pathways to regulate cytokine production and cellular activation. Several studies suggest that har...

    Authors: Jennifer L Furman and Christopher M Norris
    Citation: Journal of Neuroinflammation 2014 11:158
    Content type: Review Published on:

  5. Spinal cord injuries remain a critical issue in experimental and clinical research nowadays, and it is now well accepted that the immune response and subsequent inflammatory reactions are of significant import...

    Authors: Virginie Neirinckx, Cécile Coste, Rachelle Franzen, André Gothot, Bernard Rogister and Sabine Wislet
    Citation: Journal of Neuroinflammation 2014 11:150
    Content type: Review Published on:

  6. Alzheimer’s disease (AD) has been reconceptualized as a dynamic pathophysiological process, where the accumulation of amyloid-beta (Aβ) is thought to trigger a cascade of neurodegenerative events resulting in ...

    Authors: Eduardo Rigon Zimmer, Antoine Leuzy, Andréa Lessa Benedet, John Breitner, Serge Gauthier and Pedro Rosa-Neto
    Citation: Journal of Neuroinflammation 2014 11:120
    Content type: Review Published on:

  8. Exosomes are membrane-bound nanovesicles that are shed by cells of various lineages under normal as well as pathological conditions. Previously thought to be ‘extracellular debris’, exosomes have recently gene...

    Authors: Archana Gupta and Lynn Pulliam
    Citation: Journal of Neuroinflammation 2014 11:68
    Content type: Review Published on:

  11. Alzheimer’s disease (AD) is a major public health problem with substantial economic and social impacts around the world. The hallmarks of AD pathogenesis include deposition of amyloid β (Aβ), neurofibrillary t...

    Authors: Deborah Doens and Patricia L Fernández
    Citation: Journal of Neuroinflammation 2014 11:48
    Content type: Review Published on:

  13. Although major depressive disorder imposes a serious public health burden and affects nearly one in six individuals in developed countries over their lifetimes, there is still no consensus on its pathophysiolo...

    Authors: Joshua Bloom and Yousef Al-Abed
    Citation: Journal of Neuroinflammation 2014 11:11
    Content type: Review Published on: