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Sequence and Genome Analysis

  1. Content type: Research

    Reference assisted assembly requires the use of a reference sequence, as a model, to assist in the assembly of the novel genome. The standard method for identifying the best reference sequence for the assembly...

    Authors: Bilal Wajid, Erchin Serpedin, Mohamed Nounou and Hazem Nounou

    Citation: EURASIP Journal on Bioinformatics and Systems Biology 2012 2012:18

    Published on:

  2. Content type: Research

    Genomic studies are now being undertaken on thousands of samples requiring new computational tools that can rapidly analyze data to identify clinically important features. Inferring structural variations in ca...

    Authors: Ryan Bressler, Jake Lin, Andrea Eakin, Thomas Robinson, Richard Kreisberg, Hector Rovira, Theo Knijnenburg, John Boyle and Ilya Shmulevich

    Citation: EURASIP Journal on Bioinformatics and Systems Biology 2012 2012:15

    Published on:

  3. Content type: Research

    CpG dinucleotide clusters also referred to as CpG islands (CGIs) are usually located in the promoter regions of genes in a deoxyribonucleic acid (DNA) sequence. CGIs play a crucial role in gene expression and ...

    Authors: Rajasekhar Kakumani, Omair Ahmad and Vijay Devabhaktuni

    Citation: EURASIP Journal on Bioinformatics and Systems Biology 2012 2012:12

    Published on: