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Non-coding RNAs in physiology and disease

Non-coding RNAs, the ‘mysterious dark matter’ of the genome, have an expanding plethora of critical roles from normal development to disease progression. Ranging from long non-coding RNAs to micro RNAs, these molecules interact with RNA binding proteins to regulate a host of biological processes. How can we harness the increasing importance of non-coding RNAs and their binding partners to both understand disease and potentially treat it? This series, published in Cell Regeneration, aims to address those questions.

The articles in the series have undergone the journal’s standard peer-review process. The Editors for this series declare no competing interests.

  1. Increasing evidence indicates that microRNAs (miRNAs), endogenous short non-coding RNAs 19–24 nucleotides in length, play key regulatory roles in various biological events at the post-transcriptional level. Em...

    Authors: Young Jin Lee, Suresh Ramakrishna, Himanshu Chauhan, Won Sun Park, Seok-Ho Hong and Kye-Seong Kim
    Citation: Cell Regeneration 2016 5:2