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Beyond natural enzymes: The power of directed evolution

  1. Steroids are the most widely marketed products by the pharmaceutical industry after antibiotics. Steroid hydroxylation is one of the most important functionalizations because their derivatives enable a higher ...

    Authors: Xiaodong Zhang, Yaqin Peng, Jing Zhao, Qian Li, Xiaojuan Yu, Carlos G. Acevedo-Rocha and Aitao Li
    Citation: Bioresources and Bioprocessing 2020 7:2
  2. Organofluorines are widely used in a variety of applications, ranging from pharmaceuticals to pesticides and advanced materials. The widespread use of organofluorines also leads to its accumulation in the envi...

    Authors: Wei Tong, Qun Huang, Min Li and Jian-bo Wang
    Citation: Bioresources and Bioprocessing 2019 6:46
  3. Glucaric acid, one of the aldaric acids, has been declared a “top value-added chemical from biomass”, and is especially important in the food and pharmaceutical industries. Biocatalytic production of glucaric ...

    Authors: Hui-Hui Su, Fei Peng, Pei Xu, Xiao-Ling Wu, Min-Hua Zong, Ji-Guo Yang and Wen-Yong Lou
    Citation: Bioresources and Bioprocessing 2019 6:36
  4. Xylanases have been successfully used in food, paper, and pulp industries and are considered to be a key player in the biodegradation of xylan to valuable end products. However, most of the natural xylanases p...

    Authors: La Xiang, Yihong Lu, Hui Wang, Meixing Wang and Guimin Zhang
    Citation: Bioresources and Bioprocessing 2019 6:25
  5. Dye-decolorizing peroxidases (DyPs) are haem-containing peroxidases that show great promises in industrial biocatalysis and lignocellulosic degradation. Through the use of Escherichia coli osmotically-inducible p...

    Authors: Abdulrahman H. A. Alessa, Kang Lan Tee, David Gonzalez-Perez, Hossam E. M. Omar Ali, Caroline A. Evans, Alex Trevaskis, Jian-He Xu and Tuck Seng Wong
    Citation: Bioresources and Bioprocessing 2019 6:20
  6. A thermostable alcohol dehydrogenase from Thermoanaerobacter brockii (TbSADH) has been repurposed to perform asymmetric reduction of a series of prochiral ketones with the formation of enantio-pure secondary alco...

    Authors: Ge Qu, Beibei Liu, Yingying Jiang, Yao Nie, Huilei Yu and Zhoutong Sun
    Citation: Bioresources and Bioprocessing 2019 6:18