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Tissue oxygenation: how to measure, how much to target

Edited by:
Dr. Matthias Peter Hilty

Submission Status: Open   |   Submission Deadline: Ongoing 


Intensive Care Medicine Experimental is calling for submissions to our Collection on Tissue Oxygenation. Hemodynamic management ultimately aims to restore oxygen availability in the tissue. Some hemodynamic variables, both on a macrohemodynamic and a microcirculatory scale, remain difficult to obtain in a clinical setting, and in many instances, more research is needed to determine their relevance in a physiologic context and evaluate individualized targets. This thematic collection aims at bringing together translational and basic original research and reviews on the subject.

Guest Editors

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Matthias Peter Hilty, MD, Institute of Intensive Care Medicine, University Hospital of Zurich, Zurich, Switzerland

Matthias Hilty’s interests lie in the foundations of physiology, their application in clinical practice, and the use of advanced computational methods. His group has developed algorithms to analyze individual red blood cell paths in in-vivo dark field microscopy, as well as neuronal-network based methods to identify disease-specific alterations in the sublingual microcirculation of critically ill patients. Clinical and physiological (high-altitude) studies enable to test and validate tissue-based approaches.

Submission Guidelines

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Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via our submission system. During the submission process, under the section additional information, you will be asked whether you are submitting to a Collection, please select "Tissue oxygenation: how to measure, how much to target" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.

  1. Endothelial disorders with edema formation and microcirculatory perfusion disturbances are common in cardiac surgery with cardiopulmonary bypass (CPB) and contribute to disturbed tissue oxygenation resulting i...

    Authors: Anne M. Beukers, Anoek L. I. van Leeuwen, Roselique Ibelings, Anita M. Tuip-de Boer, Carolien S. E. Bulte, Susanne Eberl and Charissa E. van den Brom
    Citation: Intensive Care Medicine Experimental 2024 12:78
    Content type: Research Articles Published on:

  2. Circulatory shock, defined as decreased tissue perfusion, leading to inadequate oxygen delivery to meet cellular metabolic demands, remains a common condition with high morbidity and mortality. Rapid restituti...

    Authors: Anne-Aylin Sigg, Vanja Zivkovic, Jan Bartussek, Reto A. Schuepbach, Can Ince and Matthias P. Hilty
    Citation: Intensive Care Medicine Experimental 2024 12:72
    Content type: Reviews Published on:

  3. Administration of oxygen therapy is common, yet there is a lack of knowledge on its ability to prevent cellular hypoxia as well as on its potential toxicity. Consequently, the optimal oxygenation targets in cl...

    Authors: Bashar N. Hilderink, Reinier F. Crane, Bas van den Bogaard, Janesh Pillay and Nicole P. Juffermans
    Citation: Intensive Care Medicine Experimental 2024 12:37
    Content type: Research Articles Published on: