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Amino Acids

Edited by: Dr. Guoyao Wu

SpringerPlus and Dr. Guoyao Wu of Texas A&M University are proud to present an open access forum for publication of scientifically valuable manuscripts in the fields of Amino Acid, Peptide and Protein Research.

Linked to the existing Springer subscription journal Amino Acids, the Amino Acids Article Collection provides our authors with a high quality route to open access publication across a broader research scope.

Subject matters for the Article Collection include both specific and interdisciplinary coverage of the following aspects of amino acid, peptide and protein research:

Biochemistry, biomedicine, chemistry, food science, immunology, nutrition, physiology, pharmacology, reproduction, and toxicology of amino acids, peptides, and proteins, as well as genetics and bioinformatics related to synthesis, catabolism, and utilization of these fascinating substances in humans, animals (including fish), microorganisms, and plants.

We welcome direct submissions of reviews and original research articles related to amino acids, as well as their products (including peptides, proteins, peptides, and metabolites) in biomedicine, agriculture, and other disciplines of biological sciences. The Collection will also consider so-called ‘negative result’ studies.

Submission Instructions:

If your manuscript meets the aims and scope of this individual Collection, please first follow all of the SpringerPlus Submission Guidelines.

During submission, at the "Additional Information" section, please select that you are submitting to an Article Collection, and choose “Amino Acids” from the list.

Collection Articles:

  1. Research

    Co-ingestion of carbohydrate with leucine-enriched essential amino acids does not augment acute postexercise muscle protein synthesis in a strenuous exercise-induced hypoinsulinemic state

    Strenuous exercise following overnight fasting increases fat oxidation during exercise, which can modulate training adaptation. However, such exercise induces muscle protein catabolism by decreasing blood insu...

    Hiroyuki Kato, Hiromi Suzuki, Yoshiko Inoue, Tetsuya Takimoto, Katsuya Suzuki and Hisamine Kobayashi

    SpringerPlus 2016 5:1299

    Published on: 9 August 2016

  2. Research

    Modeling solubility and acid–base properties of some amino acids in aqueous NaCl and (CH3)4NCl aqueous solutions at different ionic strengths and temperatures

    New potentiometric experiments have been performed in NaCl and in (CH3)4NCl media, to determine the protonation constants, the protonation enthalpy changes and the solubility of six natural α-amino acids, namely...

    Clemente Bretti, Ottavia Giuffrè, Gabriele Lando and Silvio Sammartano

    SpringerPlus 2016 5:928

    Published on: 30 June 2016

  3. Research

    Amino acid composition in eyes from zebrafish (Danio rerio) and sardine (Sardina pilchardus) at the larval stage

    A comparative study was performed to identify differences in the amino acid composition of the eyes from zebrafish (Danio rerio) and sardine (Sardina pilchardus) larvae and their link to the environmental adaptio...

    Francesca Falco, Marco Barra, Matteo Cammarata, Angela Cuttitta, Sichao Jia, Angelo Bonanno, Salvatore Mazzola and Guoyao Wu

    SpringerPlus 2016 5:519

    Published on: 26 April 2016

  4. Research

    Identification of IgE-binding peptide and critical amino acids of Jatropha curcas allergen involved in allergenic response

    Increasing energy demand has spurred interest in the use of biofuels. Jatropha curcas (physic nut), an inedible oilseed, is a potential source of bioenergy. The seeds, however, contain allergens such as Jat c 1, ...

    Livia Maia Crespo, Natalia Deus de Oliveira, Renato Augusto Damatta, Viviane Veiga do Nascimento, Thais Pacheco Soares and Olga Lima Tavares Machado

    SpringerPlus 2016 5:454

    Published on: 14 April 2016

  5. Research

    Effect of degree of hydrolysis of whey protein on in vivo plasma amino acid appearance in humans

    Whey protein is generally found to be faster digested and to promote faster and higher increases in plasma amino acid concentrations during the immediate ~60 min following protein ingestion compared to casein....

    Jean Farup, Stine Klejs Rahbek, Adam C. Storm, Søren Klitgaard, Henry Jørgensen, Bo M. Bibby, Anja Serena and Kristian Vissing

    SpringerPlus 2016 5:382

    Published on: 31 March 2016

  6. Research

    Simultaneous detection of lysine metabolites by a single LC–MS/MS method: monitoring lysine degradation in mouse plasma

    Detection and quantification of lysine degradation metabolites in plasma is necessary for the diagnosis and follow-up of diseases such as pyridoxine-dependent epilepsy. The principal metabolites involved in t...

    Izabella A. Pena, Lygia A. Marques, Angelo B. A. Laranjeira, José A. Yunes, Marcos N. Eberlin and Paulo Arruda

    SpringerPlus 2016 5:172

    Published on: 25 February 2016

  7. Research

    Hydrolyzed fish proteins reduced activation of caspase-3 in H2O2 induced oxidative stressed liver cells isolated from Atlantic salmon (Salmo salar)

    Hydrolyzed fish proteins (H-pro) contains high concentrations of free amino acids and low molecular peptides that potentially benefit health. The following study aimed to test whether the water soluble phase o...

    M. Espe, E. Holen, J. He, F. Provan, L. Chen, K. B. Øysæd and J. Seliussen

    SpringerPlus 2015 4:658

    Published on: 31 October 2015

  8. Methodology

    Simultaneous quantification of salivary 3-hydroxybutyrate, 3-hydroxyisobutyrate, 3-hydroxy-3-methylbutyrate, and 2-hydroxybutyrate as possible markers of amino acid and fatty acid catabolic pathways by LC–ESI–MS/MS

    We have developed a highly sensitive and specific method for quantification of salivary 3-hydroxybutyrate (3HB), 3-hydroxyisobutyrate (3HIB), 3-hydroxy-3-methylbutyrate (3HMB) and 2-hydroxybutyrate (2HB), whic...

    Teruo Miyazaki, Akira Honda, Tadashi Ikegami, Junichi Iwamoto, Tadakuni Monma, Takeshi Hirayama, Yoshifumi Saito, Kouwa Yamashita and Yasushi Matsuzaki

    SpringerPlus 2015 4:494

    Published on: 15 September 2015

  9. Research

    The protection mechanism of proline from D-galactosamine hepatitis involves the early activation of ROS-eliminating pathway in the liver

    The oral pre-administration of proline, one on the non-essential amino acids, has been shown to effectively protect the liver from D-galactosamine (GalN)-induced liver injury and dramatically improve the survi...

    Yoko Obayashi, Harumi Arisaka, Shintaro Yoshida, Masato Mori and Michio Takahashi

    SpringerPlus 2015 4:199

    Published on: 28 April 2015

  10. Research

    The extracellular death factor (EDF) protects Escherichia coli by scavenging hydroxyl radicals induced by bactericidal antibiotics

    The newly discovered extracellular death factor (EDF) is a pentapeptide with the sequence NNWNN in Escherichia coli. It was reported that it participated in the cell death process mediated by toxin-antitoxin syst...

    Zhongyi Yan, Guodong Li, Yanfeng Gao, Wenjie Zhai, Yuanming Qi and Mingxia Zhai

    SpringerPlus 2015 4:182

    Published on: 16 April 2015

  11. Research

    Amino acids inhibit kynurenic acid formation via suppression of kynurenine uptake or kynurenic acid synthesis in rat brain in vitro

    The tryptophan metabolite, kynurenic acid (KYNA), is a preferential antagonist of the α7 nicotinic acetylcholine receptor at endogenous brain concentrations. Recent studies have suggested that increase of brai...

    Airi Sekine, Misaki Okamoto, Yuka Kanatani, Mitsue Sano, Katsumi Shibata and Tsutomu Fukuwatari

    SpringerPlus 2015 4:48

    Published on: 1 February 2015

  12. Software

    Rapid publication-ready MS-Word tables for two-way ANOVA

    Statistical tables are an essential component of scientific papers and reports in biomedical and agricultural sciences. Measurements in these tables are summarized as mean ± SEM for each treatment group. Resul...

    Houssein I Assaad, Yongqing Hou, Lan Zhou, Raymond J Carroll and Guoyao Wu

    SpringerPlus 2015 4:33

    Published on: 23 January 2015

  13. Research

    Taurine is absent from amino components in fruits of Opuntia ficus-indica

    Juices of edible fruits from Opuntia ficus-indica (L.) Miller, commonly named prickly pears or Indian figs, were analysed for amino acids using an automated amino acid analyser run in the high-resolution physiolo...

    Hatem Salama Mohamed Ali, Abdulrahman Saleh Al-Khalifa and Hans Brückner

    SpringerPlus 2014 3:663

    Published on: 6 November 2014

  14. Research

    Peptaibols from Trichoderma asperellum TR356 strain isolated from Brazilian soil

    The Trichoderma genus consists of a group of free-living filamentous fungi, including species able to act as biological control agents (BCAs) against pathogenic fungi. It is believed that this ability is due to s...

    João PC Brito, Marcelo HS Ramada, Mariana TQ de Magalhães, Luciano P Silva and Cirano J Ulhoa

    SpringerPlus 2014 3:600

    Published on: 13 October 2014

  15. Research

    Cardiac taurine and principal amino acids in right and left ventricles of patients with either aortic valve stenosis or coronary artery disease: the importance of diabetes and gender

    Free intracellular taurine and principal α-amino acids (glutamate, glutamine, aspartate, asparagine and alanine) are abundant in human heart. They are cellular regulators and their concentration can change in ...

    Martin Lewis, Ben Littlejohns, Hua Lin, Gianni D Angelini and M-Saadeh Suleiman

    SpringerPlus 2014 3:523

    Published on: 13 September 2014

  16. Software

    Rapid publication-ready MS-Word tables for one-way ANOVA

    Statistical tables are an important component of data analysis and reports in biological sciences. However, the traditional manual processes for computation and presentation of statistically significant result...

    Houssein I Assaad, Lan Zhou, Raymond J Carroll and Guoyao Wu

    SpringerPlus 2014 3:474

    Published on: 27 August 2014

  17. Research

    Metabolism of amino acids differs in the brains of Djungarian hamster (P. sungorus) and Roborovskii hamster (P. roborovskii)

    Djungarian hamster (P. sungorus) and Roborovskii hamster (P. roborovskii) belong to the same genus of phodopus. Roborovskii hamster shows high locomotor activity and low level of dopamine (DA) in the brain. Admin...

    Hiromi Ikeda, Takahiro Kawase, Mao Nagasawa, Vishwajit Sur Chowdhury, Shinobu Yasuo and Mitsuhiro Furuse

    SpringerPlus 2014 3:277

    Published on: 2 June 2014

  18. Short report

    Free amino acid content in breast milk of adolescent and adult mothers in Ecuador

    Because of increased incidence of teenage births and high prevalence of lactation in Latin America, we determined the patterning of free amino acids (FAAs) in breast milk of 65 primiparous Ecuadorian women of ...

    Manuel E Baldeón, Julie A Mennella, Nancy Flores, Marco Fornasini and Ana San Gabriel

    SpringerPlus 2014 3:104

    Published on: 21 February 2014

  19. Research

    Bolus ingestion of individual branched-chain amino acids alters plasma amino acid profiles in young healthy men

    Physiological conditions in humans affect plasma amino acid profiles that might have potential for medical use. Because the branched-chain amino acids (BCAAs) leucine, isoleucine and valine are used as medicin...

    Takuya Matsumoto, Koichi Nakamura, Hideki Matsumoto, Ryosei Sakai, Tomomi Kuwahara, Yoshihiro Kadota, Yasuyuki Kitaura, Juichi Sato and Yoshiharu Shimomura

    SpringerPlus 2014 3:35

    Published on: 17 January 2014

  20. Research

    Parenteral administration of twin-bearing ewes with L-arginine enhances the birth weight and brown fat stores in sheep

    The objective of this study was to evaluate the effects of parenteral administration of L-arginine (Arg) to well-fed twin-bearing ewes from day (d) 100 of pregnancy to birth on fetal growth, body composition a...

    Sue McCoard, Francisco Sales, Nina Wards, Quentin Sciascia, Mark Oliver, John Koolaard and Danitsja van der Linden

    SpringerPlus 2013 2:684

    Published on: 21 December 2013

  21. Review

    Cystine and theanine: amino acids as oral immunomodulative nutrients

    The decreases in the glutathione (GSH) level in the mouse spleen and liver after immune stimulation are suppressed by the oral administration of cystine and theanine (CT). GSH is considered to be important for...

    Shigekazu Kurihara, Tetsuro Shibakusa and Kenji AK Tanaka

    SpringerPlus 2013 2:635

    Published on: 26 November 2013

  22. Research

    Use of UPLC-ESI-MS/MS to quantitate free amino acid concentrations in micro-samples of mammalian milk

    Although free amino acids (FAA) account for a small fraction of total nitrogen in mammalian milk, they are more abundant in human milk than in most formulas, and may serve as a readily available source of amin...

    Véronique Ferchaud Roucher, Emmanuelle Desnots, Charlotte Naël, Aurore Martin Agnoux, Marie-Cécile Alexandre-Gouabau, Dominique Darmaun and Clair-Yves Boquien

    SpringerPlus 2013 2:622

    Published on: 20 November 2013

  23. Research

    A novel antifungal protein of Bacillus subtilis B25

    Bacillus subtilis B25 was isolated from banana rhizosphere soil. It has been confirmed for B25 to have stronger antagonism against Fusarium oxysporum f.sp.cubense, Additionally B25 has good inhibitory to plant p...

    Zhiqiong Tan, Baoying Lin and Rongyi Zhang

    SpringerPlus 2013 2:543

    Published on: 17 October 2013

  24. Research

    Interactive network analysis of the plasma amino acids profile in a mouse model of hyperglycemia

    Amino acids are a group of metabolites that are important substrates for protein synthesis, are important as signaling molecules and play central roles as highly connected metabolic hubs, and therefore, there ...

    Takayuki Tanaka, Taiga Mochida, Yukihiro Maki, Yasuko Shiraki, Hiroko Mori, Shirou Matsumoto, Kazutaka Shimbo, Toshihiko Ando, Kimitoshi Nakamura, Fumio Endo and Masahiro Okamoto

    SpringerPlus 2013 2:287

    Published on: 28 June 2013