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Breast Cancer

Edited by: Dr Marc Lippman

The Breast Cancer Collection is an invitation-only sister title of the Springer subscription journal, Breast Cancer Research and Treatment (BREA).

Invited submissions should choose the Breast Cancer Collection during submission, and include the invitation letter from Dr Lippman in their SpringerPlus cover letter.

For more information about how you can be considered for the Breast Cancer Collection, please speak to the editorial team at BREA.


Collection Articles:

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  1. Research

    Safety and tolerability of etirinotecan pegol in advanced breast cancer: analysis of the randomized, phase 3 BEACON trial

    New treatments with novel mechanisms of action and non-overlapping toxicities are needed for patients with metastatic breast cancer. Etirinotecan pegol (EP) is a long-acting topoisomerase-I inhibitor with a un...

    Javier Cortés, Hope S. Rugo, Chris Twelves, Ahmad Awada, Edith A. Perez, Seock-Ah Im, Carol Zhao, Ute Hoch, Denise Tomkinson, James Buchanan, Mary Tagliaferri, Alison Hannah and Joyce O’Shaughnessy

    SpringerPlus 2016 5:1033

    Published on: 8 July 2016

  2. Research

    Distant metastasis detected by routine staging in breast cancer patients participating in the national German screening programme: consequences for clinical practice

    To determine frequency of routine radiological staging of breast cancer patients diagnosed in a German Breast Cancer Screening Center from 2007 to 2014, the incidence and consequences of distant metastases det...

    Peter Rusch, Oliver Hoffmann, Anna-L. Stickelmann, Stephan Böhmer, Regine Gätje, Karl G. Krüger, Stefan Niesert, Andrea Schmidt and Rainer Kimmig

    SpringerPlus 2016 5:1010

    Published on: 7 July 2016

  3. Research

    Breast reconstruction after mastectomy at a comprehensive cancer center

    Breast reconstruction after mastectomy is an integral part of breast cancer treatment that positively impacts quality of life in breast cancer survivors. Although breast reconstruction rates have increased ove...

    Shahnjayla K. Connors, Melody S. Goodman, Terence Myckatyn, Julie Margenthaler and Sarah Gehlert

    SpringerPlus 2016 5:955

    Published on: 2 July 2016

  4. Research

    A randomized phase I trial of nanoparticle albumin-bound paclitaxel with or without mifepristone for advanced breast cancer

    Glucocorticoid receptor (GR) overexpression is associated with poor prognosis ER-negative breast cancer. GR antagonism with mifepristone increases chemotherapy-induced breast cancer cell death, therefore we co...

    Rita Nanda, Erica M. Stringer-Reasor, Poornima Saha, Masha Kocherginsky, Jean Gibson, Bernadette Libao, Philip C. Hoffman, Elias Obeid, Douglas E. Merkel, Galina Khramtsova, Maxwell Skor, Thomas Krausz, Ronald N. Cohen, Mark J. Ratain, Gini F. Fleming and Suzanne D. Conzen

    SpringerPlus 2016 5:947

    Published on: 30 June 2016

  5. Research

    Detection of a numeric value predictive of increased dose to left anterior descending coronary artery (LAD) in radiotherapy of breast cancer

    We have evaluated thoracic conformation of patients in order to derive a numeric value predictive of an increased dose to left anterior descending coronary artery (LAD), critical structure for the development ...

    R. Di Franco, V. Ravo, V. Nieddu, A. Crispo, S. Falivene, F. M. Giugliano, A. Argenone, V. Borzillo, F. Cammarota and P. Muto

    SpringerPlus 2016 5:841

    Published on: 23 June 2016

  6. Research

    Breast findings incidentally detected on body MRI

    To evaluate breast findings incidentally detected on body MRI.

    Bianca Bignotti, Giulia Succio, Francesca Nosenzo, Michela Perinetti, Licia Gristina, Stella Barbagallo, Lucia Secondini, Massimo Calabrese and Alberto Tagliafico

    SpringerPlus 2016 5:781

    Published on: 18 June 2016

  7. Research

    Worse and worse off: the impact of lymphedema on work and career after breast cancer

    Our study examines the impact of breast cancer-related lymphedema on women’s work and career. Our research addresses a significant knowledge gap regarding the additional impact of lymphedema on breast cancer s...

    John Boyages, Senia Kalfa, Ying Xu, Louise Koelmeyer, Helen Mackie, Hector Viveros, Lucy Taksa and Paul Gollan

    SpringerPlus 2016 5:657

    Published on: 17 May 2016

  8. Research

    Luminal B breast cancer subtype displays a dicotomic epigenetic pattern

    Luminal B breast tumors have aggressive clinical and biological features, and constitute the most heterogeneous molecular subtype, both clinically and molecularly. Unfortunately, the immunohistochemistry corre...

    Naiara G. Bediaga, Elena Beristain, Borja Calvo, María A. Viguri, Borja Gutierrez-Corres, Ricardo Rezola, Irune Ruiz-Diaz, Isabel Guerra and Marian M. de Pancorbo

    SpringerPlus 2016 5:623

    Published on: 14 May 2016

  9. Research

    Assessment of psychosocial factors and distress in women having adjuvant endocrine therapy for breast cancer: the relationship among emotional distress and patient and treatment-related factors

    The aims of this study were to comprehensively describe the psychosocial and medical characteristics of women who initiated tamoxifen or aromatase inhibitors for breast cancer and to compare levels of emotiona...

    Ozturk Ates, Cem Soylu, Taner Babacan, Furkan Sarici, Neyran Kertmen, Deborah Allen, Ali Riza Sever and Kadri Altundag

    SpringerPlus 2016 5:486

    Published on: 19 April 2016

  10. Research

    Polymorphisms in DNA repair and oxidative stress genes associated with pre-treatment cognitive function in breast cancer survivors: an exploratory study

    The purpose of this exploratory candidate gene association study was to examine relationships between polymorphisms in oxidative stress and DNA repair genes and pre-adjuvant therapy cognitive function (CF) in ...

    Theresa A. Koleck, Catherine M. Bender, Susan M. Sereika, Adam M. Brufsky, Barry C. Lembersky, Priscilla F. McAuliffe, Shannon L. Puhalla, Priya Rastogi and Yvette P. Conley

    SpringerPlus 2016 5:422

    Published on: 9 April 2016

  11. Research

    Survival in patients with non-metastatic breast cancer treated with adjuvant trastuzumab in clinical practice

    The NSABP Trial B-31 and NCCTG Trial N9831 (B-31/N9831 trials, Romond et al. in N Engl J Med 353:1673–84, 2005. doi:10.​1056/​NEJMoa052122; Perez et al. ...

    Christopher M. Gallagher, Kenneth More, Anthony Masaquel, Tripthi Kamath, Annie Guerin, Raluca Ionescu-Ittu, Roy Nitulescu, Marjolaine Gauthier-Loiselle, Nicholas Sicignano, Elizabeth Butts, Eric Q. Wu and Brian Barnett

    SpringerPlus 2016 5:395

    Published on: 31 March 2016

  12. Research

    Isolated radial scar diagnosis by core-needle biopsy: Is surgical excision necessary?

    Radial scar and radial sclerosis (RS) are considered benign breast lesions with proliferative features. There is sparse literature on frequency of cancer upgrade in these patients without atypical features fou...

    Elizabeth Min Hui Kim, Andrea Hankins, Jamie Cassity, Dennis McDonald, Barbara White, Ron Rowberry, Sharon Dutton and Claire Snyder

    SpringerPlus 2016 5:398

    Published on: 31 March 2016

  13. Research

    cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancer

    Epidemiologic studies have associated obesity with increased risk of the aggressive basal-like breast cancer (BBC) subtype. Hepatocyte growth factor (HGF) signaling through its receptor, cMET, is elevated in o...

    Alyssa J. Cozzo, Sneha Sundaram, Ottavia Zattra, Yuanyuan Qin, Alex J. Freemerman, Luma Essaid, David B. Darr, Stephanie A. Montgomery, Kirk K. McNaughton, J. Ashley Ezzell, Joseph A. Galanko, Melissa A. Troester and Liza Makowski

    SpringerPlus 2016 5:348

    Published on: 19 March 2016

  14. Research

    A phase II, multicenter, single-arm trial of eribulin as first-line chemotherapy for HER2-negative locally advanced or metastatic breast cancer

    The treatment goals for metastatic breast cancer (MBC) are prolonging survival and improving the quality of life. Eribulin, a non-taxane tubulin inhibitor, demonstrated improved survival in previous studies an...

    Tsutomu Takashima, Shinya Tokunaga, Seika Tei, Shigehiko Nishimura, Hidemi Kawajiri, Shinichiro Kashiwagi, Shigehito Yamagata, Satoru Noda, Takeo Nishimori, Yoko Mizuyama, Takeshi Sunami, Kenji Tezuka, Katsumi Ikeda, Yoshinari Ogawa, Naoyoshi Onoda, Tetsuro Ishikawa…

    SpringerPlus 2016 5:164

    Published on: 24 February 2016

  15. Research

    Role of patient and tumor characteristics in sentinel lymph node metastasis in patients with luminal early breast cancer: an observational study

    Predicting the risk of sentinel lymph node (SLN) metastasis is important for clinical decision-making in the setting of early breast cancer (EBC). This study is aimed to identify tumor and patient characterist...

    Nicla La Verde, Elena Biagioli, Chiara Gerardi, Andrea Cordovana, Chiara Casiraghi, Irene Floriani, Elena Bernardin, Gabriella Farina, Serena Di Cosimo, Maria Chiara Dazzani and Giorgio Gherardi

    SpringerPlus 2016 5:114

    Published on: 3 February 2016

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