Guest Editor: Professor Mahin Khatami, PhD
Clinical and Translational Medicine invites you to submit to our new thematic series, ‘Cancer bioenergetics and translational medicine’.
Maintenance of health involves fascinating precise biological laws for wear and tear, degeneration, repair and regeneration of tissues and organ systems throughout life. Cross communication between, and among, physio-immune-neuro-pathologic mechanisms that follow ‘biological laws’ require differential energy-dependent events. Features of age-associated chronic diseases, such as metabolic syndromes, diabetes and cardiovascular complications, neurodegenerative and autoimmune diseases or site-specific cancers, are associated with degrees of disruption in energy-requirements and deficiencies or retardation of activities of control switches at cell, tissue and organ levels.
Mitochondrial function in supplying energy to maintain the balance between the two biologically opposing arms of Yin and Yang of effective immunity are fundamental for the maintenance of health. Effective translational medicine for cost-effective cancer research and therapy requires systematic integration of worthy information on biological defects involved in multistep chronic diseases or cancer.
The Editors invite submissions for this series that will emphasize the role of bioenergetics in cancer, including articles on the following topics: bioenergetics of mitochondria, and ribosomes in health and age-associated diseases, such as cancer; stimuli-induced oxidative metabolism of innate and adaptive immune cell responses; pyruvate carrier shuttles, TCA cycle and oxidative metabolism; oxidative stress-induced mitophagy or autophagy, Warburg effect and glucose and solute transport or metabolism, membrane proteins function, e.g., aquoporins, Na+/K+ , H+ or Ca+2 active transporters, exchangers ATPases, kinases, hydrolases; mTORs protein/enzyme synergies and interactions including NAD+-dependent or ROS-induced pathways; and metabolism of branched and aromatic amino acids and protein biosynthesis.
Manuscripts should be formatted according to our submission guidelines and submitted via the online submission system. In the submission system please make sure the correct collection title is chosen on the additional information tab. Please also indicate clearly in the covering letter that the manuscript is to be considered for the ‘Cancer bioenergetics and translational medicine’ series.
For further information, please email firstname.lastname@example.org.