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Developmental Hematopoiesis and Stem Cells

Leading Editors:
Dr. Feng Liu (State Key Laboratory of Membrane Biology, Chinese Academy of Sciences, China)
Dr. Zilong Wen (Division of Life Science, Hong Kong University of Science and Technology, China)
Dr. Ling Li (Beckman Research Institute of City of Hope, USA)

A thematic series in Cell Regeneration.

The hematopoietic system is a paradigm for stem cell research. Hematopoietic stem cells (HSCs) are a population of multipotent cells that can self-renew and differentiate into all blood lineages, maintaining lifelong blood production. The development of HSCs and their derivatives must be tightly controlled, which involves a complex of extrinsic signaling and intrinsic factors. A better understanding of the ontogeny of HSCs and their regulation could improve de novo generation and expansion of functional HSCs, and will provide useful insights for their applications in regenerative medicine.

To highlight recent progress on HSC research, Cell Regeneration is inviting submissions to its upcoming special issue on “Developmental hematopoiesis and stem cells”. 

We will especially welcome Research, Method and Review submissions, including (but not limited to) the following areas:

  • Developmental hematopoiesis
  • Hematopoiesis malignancies
  • Single cell omics in hematopoiesis
  • Lineage tracing in hematopoiesis
  • HSC culture and organoid

The Editor-in-Chief of Cell Regeneration will review all submissions prior to peer review and may reject any of them that do not fit the scope of the journal or do not meet the journal's standards for peer review. All articles of Thematic Series will undergo full, independent peer review, in line with the journal's ethical and editorial policies, outlined in its submission guidelines. There is no guarantee of acceptance, even for commissioned or invited papers. The journal’s Editor-in-Chief has a final authority on editorial content.

  1. Human hematopoiesis starts at early yolk sac and undergoes site- and stage-specific changes over development. The intrinsic mechanism underlying property changes in hematopoiesis ontogeny remains poorly unders...

    Authors: Fei Li, Yanling Zhu, Tianyu Wang, Jun Tang, Yuhua Huang, Jiaming Gu, Yuchan Mai, Mingquan Wang, Zhishuai Zhang, Jiaying Ning, Baoqiang Kang, Junwei Wang, Tiancheng Zhou, Yazhou Cui and Guangjin Pan
    Citation: Cell Regeneration 2024 13:9
  2. Human pluripotent stem cells (hPSCs) have been suggested as a potential source for the production of blood cells for clinical application. In two decades, almost all types of blood cells can be successfully ge...

    Authors: Haiqiong Zheng, Yijin Chen, Qian Luo, Jie Zhang, Mengmeng Huang, Yulin Xu, Dawei Huo, Wei Shan, Ruxiu Tie, Meng Zhang, Pengxu Qian and He Huang
    Citation: Cell Regeneration 2023 12:31

    The Correction to this article has been published in Cell Regeneration 2023 12:32

  3. Hematopoietic stem cells (HSCs) are critical for the treatment of a variety of hematological diseases. However, the low number of HSCs lead to the clinical application difficult. To gain more functional human ...

    Authors: Guixian Liang and Feng Liu
    Citation: Cell Regeneration 2023 12:18
  4. EAF1 and EAF2, the eleven-nineteen lysine-rich leukemia (ELL)-associated factors which can assemble to the super elongation complex (AFF1/4, AF9/ENL, ELL, and P-TEFb), are reported to participate in RNA polyme...

    Authors: WenYe Liu, ShuHui Lin, LingYa Li, ZhiPeng Tai and Jing-Xia Liu
    Citation: Cell Regeneration 2023 12:10
  5. Myelopoiesis is the process in which the mature myeloid cells, including monocytes/macrophages and granulocytes, are developed. Irregular myelopoiesis may cause and deteriorate a variety of hematopoietic malig...

    Authors: Yang-Xi Hu and Qing Jing
    Citation: Cell Regeneration 2023 12:2