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Gene Editing and Stem Cells

Leading Editors:
Jinsong Li (CAS Center for Excellence in Molecular Cell Science, China) and Liangxue Lai (Guangzhou Institute of Biomedicine and Health, CAS, China)

A thematic series in Cell Regeneration.


Stem cells are able to differentiate into specialized cell types, so have become a functional platform for the study and treatment of disease. Advances in gene editing technology such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), particularly the CRISPR/Cas9 system, have had a great impact on basic science, medical application. The combination of these two technologies holds great promise for more accurate disease models and precise cell therapies. 

To present the recent advances in the technology and application of gene editing and stem cells, Cell Regeneration invite you and/or members of your research team to submit manuscript(s) for this special issue including original research articles, methodology articles, resource articles, commentary articles, review articles, and more.

The Editor-in-Chief of Cell Regeneration will review all submissions prior to peer review and may reject any of them that do not fit the scope of the journal or do not meet the journal's standards for peer review. All articles of Thematic Series will undergo full, independent peer review, in line with the journal's ethical and editorial policies, outlined in its submission guidelines. There is no guarantee of acceptance, even for commissioned or invited papers. The journal’s Editor-in-Chief has a final authority on editorial content.

  1. The rapidly developmental RNA-guided CRISPR/Cas system is a powerful tool for RNA and DNA editing in a variety of cells from different species and makes a great contribution to gene function research, disease ...

    Authors: Yanxia Gao, Kexin Gao and Hui Yang
    Citation: Cell Regeneration 2020 9:12

    The Correction to this article has been published in Cell Regeneration 2021 10:35

  2. Transposable elements constitute about half of the mammalian genome, and can be divided into two classes: the class I (retrotransposons) and the class II (DNA transposons). A few hundred types of retrotranspos...

    Authors: Jingwen Wang, Junjiu Huang and Guang Shi
    Citation: Cell Regeneration 2020 9:4