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Total Body PET

  1. Low-dose ungated CT is commonly used for total-body PET attenuation and scatter correction (ASC). However, CT-based ASC (CT-ASC) is limited by radiation dose risks of CT examinations, propagation of CT-based a...

    Authors: Hao Sun, Yanchao Huang, Debin Hu, Xiaotong Hong, Yazdan Salimi, Wenbing Lv, Hongwen Chen, Habib Zaidi, Hubing Wu and Lijun Lu
    Citation: EJNMMI Physics 2024 11:66
  2. Long axial field-of-view (LAFOV) PET/CT systems enable PET/CT scans with reduced injected activities because of improved sensitivity. With this study, we aimed to examine the foetal radiation dose from an 18F-FDG...

    Authors: Charlotte L. C. Smith, Maqsood Yaqub, Ruud H. H. Wellenberg, Jelijn J. Knip, Ronald Boellaard and Gerben J. C. Zwezerijnen
    Citation: EJNMMI Physics 2024 11:45
  3. Accurate image-derived input function (IDIF) from highly sensitive large axial field of view (LAFOV) PET/CT scanners could avoid the need of invasive blood sampling for kinetic modelling. The aim is to validat...

    Authors: Xavier Palard-Novello, Denise Visser, Nelleke Tolboom, Charlotte L. C. Smith, Gerben Zwezerijnen, Elsmarieke van de Giessen, Marijke E. den Hollander, Frederik Barkhof, Albert D. Windhorst, Bart NM van Berckel, Ronald Boellaard and Maqsood Yaqub
    Citation: EJNMMI Physics 2024 11:25
  4. Conventional PET/CT imaging reconstruction is typically performed using voxel size of 3.0–4.0 mm in three axes. It is hypothesized that a smaller voxel sizes could improve the accuracy of small lesion detectio...

    Authors: Chi Qi, Xiuli Sui, Haojun Yu, Siyang Wang, Yan Hu, Hongyan Sun, Xinlan Yang, Yihan Wang, Yun Zhou and Hongcheng Shi
    Citation: EJNMMI Physics 2024 11:17
  5. This study aims to decrease the scan time and enhance image quality in pediatric total-body PET imaging by utilizing multimodal artificial intelligence techniques.

    Authors: Qiyang Zhang, Yingying Hu, Chao Zhou, Yumo Zhao, Na Zhang, Yun Zhou, Yongfeng Yang, Hairong Zheng, Wei Fan, Dong Liang and Zhanli Hu
    Citation: EJNMMI Physics 2024 11:1
  6. Although a new generation of tomographs with a longer axial field-of-view called total-body PET have been developed, they are not widely utilized due to their high cost compared to conventional scanners. The n...

    Authors: Meysam Dadgar, Jens Maebe, Maya Abi Akl, Boris Vervenne and Stefaan Vandenberghe
    Citation: EJNMMI Physics 2023 10:75
  7. Alongside the benefits of Total-Body imaging modalities, such as higher sensitivity, single-bed position, low dose imaging, etc., their final construction cost prevents worldwide utilization. The main aim of t...

    Authors: M. Dadgar, S. Parzych, J. Baran, N. Chug, C. Curceanu, E. Czerwiński, K. Dulski, K. Elyan, A. Gajos, B. C. Hiesmayr, Ł. Kapłon, K. Klimaszewski, P. Konieczka, G. Korcyl, T. Kozik, W. Krzemien…
    Citation: EJNMMI Physics 2023 10:62
  8. In light of the milestones achieved in PET design so far, further sensitivity improvements aim to optimise factors such as the dose, throughput, and detection of small lesions. While several longer axial field...

    Authors: Maya Abi-Akl, Meysam Dadgar, Yassine Toufique, Othmane Bouhali and Stefaan Vandenberghe
    Citation: EJNMMI Physics 2023 10:37
  9. Total-body PET scanners with axial field of views (FOVs) longer than 1 m enable new applications to study multiple organs (e.g., the brain-gut-axis) simultaneously. As the spatial resolution and the associated...

    Authors: Julia G. Mannheim, Ivo Rausch, Maurizio Conti, Christian la Fougère and Fabian P. Schmidt
    Citation: EJNMMI Physics 2023 10:33
  10. The Jagiellonian Positron Emission Tomograph is the 3-layer prototype of the first scanner based on plastic scintillators, consisting of 192 half-metre-long strips with readouts at both ends. Compared to cryst...

    Authors: S. Sharma, J. Baran, N. Chug, C. Curceanu, E. Czerwiński, M. Dadgar, K. Dulski, K. Eliyan, A. Gajos, N. Gupta-Sharma, B. C. Hiesmayr, K. Kacprzak, Ł. Kapłon, K. Klimaszewski, P. Konieczka, G. Korcyl…
    Citation: EJNMMI Physics 2023 10:28
  11. Highly sensitive digital total-body PET/CT scanners (uEXPLORER) have great potential for clinical applications and fundamental research. Given their increasing sensitivity, low-dose scanning or snapshot imagin...

    Authors: Yanchao Huang, Meng Wang, Li Jiang, Lijuan Wang, Li Chen, Qiaoyu Wang, Jiatai Feng, Jingyi Wang, Wanbang Xu, Hubing Wu and Yanjiang Han
    Citation: EJNMMI Physics 2023 10:14
  12. Recently, total-body PET/CT systems with an extended axial field-of-view (aFOV) became commercially available which allow acquiring physiologic information of multiple organs simultaneously. However, the nomin...

    Authors: Ivo Rausch, Julia G. Mannheim, Jürgen Kupferschläger, Christian la Fougère and Fabian P. Schmidt
    Citation: EJNMMI Physics 2022 9:87
  13. Excellent performance characteristics of the Vision Quadra PET/CT, e.g. a substantial increase in sensitivity, allow for precise measurements of image-derived input functions (IDIF) and tissue time activity cu...

    Authors: Joyce van Sluis, Johannes H. van Snick, Adrienne H. Brouwers, Walter Noordzij, Rudi A. J. O. Dierckx, Ronald J. H. Borra, Adriaan A. Lammertsma, Andor W. J. M. Glaudemans, Riemer H. J. A. Slart, Maqsood Yaqub, Charalampos Tsoumpas and Ronald Boellaard
    Citation: EJNMMI Physics 2022 9:74
  14. Efforts have been made both to avoid invasive blood sampling and to shorten the scan duration for dynamic positron emission tomography (PET) imaging. A total-body scanner, such as the uEXPLORER PET/CT, can rel...

    Authors: Zhenguo Wang, Yaping Wu, Xiaochen Li, Yan Bai, Hongzhao Chen, Jie Ding, Chushu Shen, Zhanli Hu, Dong Liang, Xin Liu, Hairong Zheng, Yongfeng Yang, Yun Zhou, Meiyun Wang and Tao Sun
    Citation: EJNMMI Physics 2022 9:63
  15. The total-body positron emission tomography (PET) scanner provides an unprecedented opportunity to scan the whole body simultaneously, thanks to its long axial field of view and ultrahigh temporal resolution. ...

    Authors: Tao Sun, Yaping Wu, Wei Wei, Fangfang Fu, Nan Meng, Hongzhao Chen, Xiaochen Li, Yan Bai, Zhenguo Wang, Jie Ding, Debin Hu, Chaojie Chen, Zhanli Hu, Dong Liang, Xin Liu, Hairong Zheng…
    Citation: EJNMMI Physics 2022 9:62
  16. The present study aimed to explore the boundary of acquisition time and propose an optimized acquisition time range for total-body positron emission tomography (PET)/computed tomography (CT) oncological imagin...

    Authors: Yibo He, Yushen Gu, Haojun Yu, Bing Wu, Siyang Wang, Hui Tan, Yanyan Cao, Shuguang Chen, Xiuli Sui, Yiqiu Zhang and Hongcheng Shi
    Citation: EJNMMI Physics 2022 9:45