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Mechanism of kidney disease development and CKD associated morbidities

  1. Children with chronic kidney disease (CKD) suffer from inflammation and reactive metabolite-induced stress, which massively accelerates tissue and vascular aging. Peritoneal dialysis (PD) is the preferred dial...

    Authors: Maria Bartosova, Sotirios G. Zarogiannis and Claus Peter Schmitt
    Citation: Molecular and Cellular Pediatrics 2022 9:9
  2. Idiopathic nephrotic syndrome (INS) in children is characterized by massive proteinuria and hypoalbuminemia and usually responds well to steroids. However, relapses are frequent, which can require multi-drug t...

    Authors: Agnes Hackl, Seif El Din Abo Zed, Paul Diefenhardt, Julia Binz-Lotter, Rasmus Ehren and Lutz Thorsten Weber
    Citation: Molecular and Cellular Pediatrics 2021 8:18
  3. Cardiovascular complications are the major cause of the marked morbidity and mortality associated with chronic kidney disease (CKD). The classical cardiovascular risk factors such as diabetes and hypertension ...

    Authors: Julia Schlender, Felix Behrens, Victoria McParland, Dominik Müller, Nicola Wilck, Hendrik Bartolomaeus and Johannes Holle
    Citation: Molecular and Cellular Pediatrics 2021 8:17
  4. DSTYK encodes dual serine/threonine and tyrosine protein kinase. DSTYK has been associated with autosomal-dominant congenital anomalies of the kidney and urinary tract and with autosomal-recessive hereditary spas...

    Authors: Clara Vidic, Marcin Zaniew, Szymon Jurga, Holger Thiele, Heiko Reutter and Alina C. Hilger
    Citation: Molecular and Cellular Pediatrics 2021 8:13
  5. Chronic kidney disease (CKD) is associated with distinct alterations in mineral metabolism in children and adults resulting in multiple organ dysfunctions. Children with advanced CKD often suffer from impaired...

    Authors: Maren Leifheit-Nestler and Dieter Haffner
    Citation: Molecular and Cellular Pediatrics 2021 8:12
  6. After pediatric kidney transplantation, immunosuppressive therapy is given to avoid acute and chronic rejections. However, the immunosuppression causes an increased risk of severe viral complications and bacte...

    Authors: Thurid Ahlenstiel-Grunow and Lars Pape
    Citation: Molecular and Cellular Pediatrics 2021 8:8

    The Correction to this article has been published in Molecular and Cellular Pediatrics 2021 8:14