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Mechanism of kidney disease development and CKD associated morbidities

  1. Idiopathic nephrotic syndrome (INS) in children is characterized by massive proteinuria and hypoalbuminemia and usually responds well to steroids. However, relapses are frequent, which can require multi-drug t...

    Authors: Agnes Hackl, Seif El Din Abo Zed, Paul Diefenhardt, Julia Binz-Lotter, Rasmus Ehren and Lutz Thorsten Weber

    Citation: Molecular and Cellular Pediatrics 2021 8:18

    Content type: Review

    Published on:

  2. Cardiovascular complications are the major cause of the marked morbidity and mortality associated with chronic kidney disease (CKD). The classical cardiovascular risk factors such as diabetes and hypertension ...

    Authors: Julia Schlender, Felix Behrens, Victoria McParland, Dominik Müller, Nicola Wilck, Hendrik Bartolomaeus and Johannes Holle

    Citation: Molecular and Cellular Pediatrics 2021 8:17

    Content type: Review

    Published on:

  3. DSTYK encodes dual serine/threonine and tyrosine protein kinase. DSTYK has been associated with autosomal-dominant congenital anomalies of the kidney and urinary tract and with autosomal-recessive hereditary spas...

    Authors: Clara Vidic, Marcin Zaniew, Szymon Jurga, Holger Thiele, Heiko Reutter and Alina C. Hilger

    Citation: Molecular and Cellular Pediatrics 2021 8:13

    Content type: Research

    Published on:

  4. Chronic kidney disease (CKD) is associated with distinct alterations in mineral metabolism in children and adults resulting in multiple organ dysfunctions. Children with advanced CKD often suffer from impaired...

    Authors: Maren Leifheit-Nestler and Dieter Haffner

    Citation: Molecular and Cellular Pediatrics 2021 8:12

    Content type: Mini review

    Published on:

  5. After pediatric kidney transplantation, immunosuppressive therapy is given to avoid acute and chronic rejections. However, the immunosuppression causes an increased risk of severe viral complications and bacte...

    Authors: Thurid Ahlenstiel-Grunow and Lars Pape

    Citation: Molecular and Cellular Pediatrics 2021 8:8

    Content type: Mini review

    Published on:

    The Correction to this article has been published in Molecular and Cellular Pediatrics 2021 8:14