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Recent advances in pediatric lung diseases

  1. Mini review

    Early origins of asthma (and allergy)

    Asthma is the most common chronic disease starting in childhood and persisting into adulthood in many cases. During childhood, different forms of asthma and wheezing disorders exist that can be discriminated b...

    Michael Kabesch

    Molecular and Cellular Pediatrics 2016 3:31

    Published on: 10 August 2016

  2. Mini review

    Vitamin A-retinoid signaling in pulmonary development and disease

    Retinoic acid (RA), the active form of vitamin A, regulates key developmental processes in multiple organs. In the developing lung, RA is crucial for normal growth and differentiation of airways. Disruption in...

    Hector A. Marquez and Wellington V. Cardoso

    Molecular and Cellular Pediatrics 2016 3:28

    Published on: 1 August 2016

  3. Mini review

    The puzzle of immune phenotypes of childhood asthma

    Asthma represents the most common chronic childhood disease worldwide. Whereas preschool children present with wheezing triggered by different factors (multitrigger and viral wheeze), clinical asthma manifesta...

    Katja Landgraf-Rauf, Bettina Anselm and Bianca Schaub

    Molecular and Cellular Pediatrics 2016 3:27

    Published on: 28 July 2016

  4. Mini review

    Mechanism of human rhinovirus infections

    About 150 human rhinovirus serotypes are responsible for more than 50 % of recurrent upper respiratory infections. Despite having similar 3D structures, some bind members of the low-density lipoprotein recepto...

    Dieter Blaas and Renate Fuchs

    Molecular and Cellular Pediatrics 2016 3:21

    Published on: 1 June 2016

  5. Mini review

    Alveologenesis: key cellular players and fibroblast growth factor 10 signaling

    Alveologenesis is the last stage in lung development and is essential for building the gas-exchanging units called alveoli. Despite intensive lung research, the intricate crosstalk between mesenchymal and epit...

    Cho-Ming Chao, Alena Moiseenko, Klaus-Peter Zimmer and Saverio Bellusci

    Molecular and Cellular Pediatrics 2016 3:17

    Published on: 21 April 2016

  6. Mini review

    Can the preterm lung recover from perinatal stress?

    After birth, adequate lung function is necessary for the successful adaptation of a preterm baby. Both prenatal and postnatal insults and therapeutic interventions have an immediate effect on lung function and...

    Matthias C. Hütten, Tim G. A. M. Wolfs and Boris W. Kramer

    Molecular and Cellular Pediatrics 2016 3:15

    Published on: 13 April 2016

  7. Mini review

    Update on host-pathogen interactions in cystic fibrosis lung disease

    Bacterial and fungal infections are hallmarks of cystic fibrosis (CF) lung disease. In the era of long-term inhaled antibiotics and increasing CF patient survival, new “emerging” pathogens are detected in CF a...

    Andreas Hector, Nina Frey and Dominik Hartl

    Molecular and Cellular Pediatrics 2016 3:12

    Published on: 23 February 2016

  8. Mini review

    Mesenchymal stem/stromal cells—a key mediator for regeneration after perinatal morbidity?

    Perinatal complications in both term- and preterm-born infants are a leading cause of neonatal morbidities and mortality. Infants face different challenges in the neonatal intensive care unit with long-term mo...

    Martin Mueller, Tim G. A. Wolfs, Andreina Schoeberlein, Antonio W. D. Gavilanes, Daniel Surbek and Boris W. Kramer

    Molecular and Cellular Pediatrics 2016 3:6

    Published on: 11 February 2016

  9. Mini review

    The role of hypoxia in intestinal inflammation

    Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disease of the intestine. IBD is a multifactorial disorder, and IBD-associated genes are critical in innate immune response, inflammatory re...

    Yatrik M. Shah

    Molecular and Cellular Pediatrics 2016 3:1

    Published on: 26 January 2016